Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990915 | 0.80 | LMNA (0.42) | ALDH1A1SMN1; SMN2LMNAMAPTL3MBTL1 | |
| SCHEMBL7991427 | 0.79 | HRH3 (0.37) | LMNAPOLBMAPTL3MBTL1 | |
| SCHEMBL7976831 | 0.78 | FFAR1 (0.37) | — | |
| Oxalic Acid SCHEMBL7991431 | 0.76 | SMN1; SMN2 (0.45) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL4383470 | 0.76 | LMNA (0.45) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL7987121 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL7988354 | 0.72 | SMN1; SMN2 (0.45) | RAB9ASMN1; SMN2NPC1MAPTL3MBTL1 | |
| SCHEMBL4378007 | 0.69 | KMT2A (0.48) | ALDH1A1 | |
| SCHEMBL6861934 | 0.68 | HAO1 (0.34) | RAB9ANPC1 | |
| SCHEMBL19001352 | 0.68 | CA12 (0.64) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |