Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990915 | 0.88 | LMNA (0.42) | HRH3MEN1KMT2A | |
| SCHEMBL7991427 | 0.81 | HRH3 (0.37) | KCNH2HRH3 | |
| SCHEMBL7991347 | 0.79 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL7987121 | 0.78 | SMN1; SMN2 (0.46) | KCNH2HRH3MEN1KMT2A | |
| SCHEMBL7991433 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL7988354 | 0.74 | SMN1; SMN2 (0.45) | HRH3MEN1KMT2A | |
| SCHEMBL15130145 | 0.73 | HRH3 (0.47) | HRH3 | |
| SCHEMBL7990787 | 0.73 | MCL1 (0.48) | MEN1KMT2A | |
| SCHEMBL6861934 | 0.72 | HAO1 (0.34) | KCNH2HRH3 | |
| SCHEMBL4390109 | 0.72 | KCNH2 (0.39) | KCNH2HRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | claimed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |