Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7991431 | 0.94 | SMN1; SMN2 (0.45) | LMNAALDH1A1SMN1; SMN2HTTRAB9A | |
| SCHEMBL8795290 | 0.85 | ALDH1A1 (0.41) | LMNAALDH1A1L3MBTL1CA12CA1 | |
| SCHEMBL4379847 | 0.80 | HTR2A (0.42) | LMNAALDH1A1SMN1; SMN2HTTRAB9A | |
| SCHEMBL7987297 | 0.78 | HRH3 (0.54) | LMNAALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4380966 | 0.78 | NQO1 (0.45) | LMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7991433 | 0.76 | ALDH1A1 (0.43) | LMNAALDH1A1SMN1; SMN2HTTRAB9A | |
| SCHEMBL4386689 | 0.75 | LMNA (0.45) | LMNAALDH1A1SMN1; SMN2HTTRAB9A | |
| SCHEMBL7961327 | 0.75 | RAB9A (0.43) | LMNAALDH1A1HTTRAB9AHTR2A | |
| SCHEMBL4376187 | 0.75 | L3MBTL1 (0.59) | LMNAALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL7988365 | 0.74 | MEN1 (0.48) | LMNAALDH1A1SMN1; SMN2HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |