Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988354 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL7991433 | 0.76 | ALDH1A1 (0.43) | SMN1; SMN2L3MBTL1NPC1ALDH1A1RAB9A | |
| Oxalic Acid SCHEMBL7987116 | 0.71 | L3MBTL1 (0.49) | SMN1; SMN2L3MBTL1KCNH2NPC1MEN1 | |
| SCHEMBL4378007 | 0.71 | KMT2A (0.48) | MEN1KMT2AALDH1A1HRH3 | |
| SCHEMBL4394315 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1KCNH2MEN1KMT2A | |
| SCHEMBL2697602 | 0.65 | L3MBTL1 (0.59) | SMN1; SMN2L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL15908103 | 0.65 | GAA (0.62) | SMN1; SMN2L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL7064531 | 0.64 | LMNA (0.70) | L3MBTL1KMT2AALDH1A1GAARAB9A | |
| SCHEMBL10272586 | 0.64 | HIF1A (0.57) | SMN1; SMN2KCNH2NPC1ALDH1A1HRH3 | |
| SCHEMBL313373 | 0.64 | DRD2 (0.64) | L3MBTL1KCNH2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |