Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.43 |
| ▸ | PARN | O95453 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | CBFB | Q13951 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985494 | 0.91 | CNOT7 (0.52) | CNOT7PARNMETAP2METAP1SMN1; SMN2 | |
| SCHEMBL7974054 | 0.89 | EGLN1 (0.44) | CNOT7PARNMETAP2METAP1CBFB | |
| SCHEMBL7991792 | 0.89 | ALDH1A1 (0.44) | CNOT7PARNMETAP2METAP1CBFB | |
| SCHEMBL7991661 | 0.89 | ABCC8 (0.45) | CNOT7PARNMETAP2METAP1SMN1; SMN2 | |
| SCHEMBL7984720 | 0.85 | CNOT7 (0.48) | CNOT7PARNSMN1; SMN2LMNAHTT | |
| SCHEMBL7992180 | 0.84 | SMN1; SMN2 (0.45) | CNOT7PARNMETAP2METAP1CBFB | |
| SCHEMBL7991530 | 0.83 | HPGD (0.48) | METAP2METAP1CBFBSMN1; SMN2LMNA | |
| SCHEMBL7985827 | 0.82 | CNOT7 (0.49) | CNOT7PARNSMN1; SMN2LMNAHTT | |
| SCHEMBL7974009 | 0.82 | METAP2 (0.41) | CNOT7PARNMETAP2METAP1CBFB | |
| SCHEMBL7985461 | 0.82 | TP53 (0.48) | LMNANPC1RAB9AGAANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |