Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 2/20 | 0.56 |
| ▸ | BRS3 | P32247 | 4/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | GCGR | P47871 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995385 | 0.88 | MMP2 (0.51) | RNASEH1BRS3NTRK1MAPK13GCGR | |
| SCHEMBL7992103 | 0.81 | GPR84 (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7991774 | 0.79 | RAB9A (0.52) | KDM4EMEN1GAAKMT2ANPC1 | |
| SCHEMBL7978027 | 0.76 | KDM4E (0.67) | RNASEH1MAPK14ALDH1A1HPGDKDM4E | |
| SCHEMBL7977822 | 0.75 | KDM4E (0.47) | ALDH1A1HPGDKDM4EMEN1GLA | |
| SCHEMBL6357709 | 0.74 | RNASEH1 (0.60) | RNASEH1BRS3NPC1RAB9A | |
| SCHEMBL7989975 | 0.73 | DHODH (0.61) | ALDH1A1HPGDKDM4EMEN1GLA | |
| SCHEMBL20376630 | 0.72 | KDM4E (0.47) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL7977763 | 0.71 | CTRC (0.53) | MAPK14ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL7995189 | 0.71 | KDM4E (0.43) | ALDH1A1HPGDKDM4EMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |