Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | RNASEH1 | O60930 | 2/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | BRS3 | P32247 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992155 | 0.88 | RNASEH1 (0.56) | RNASEH1NTRK1MAPK14MAPK13GCGR | |
| SCHEMBL7995274 | 0.81 | ALDH1A1 (0.42) | RNASEH1GCGRALDH1A1HPGDHSD17B10 | |
| SCHEMBL7977922 | 0.81 | ALDH1A1 (0.42) | RNASEH1GCGRALDH1A1HPGDHSD17B10 | |
| SCHEMBL7991774 | 0.79 | RAB9A (0.52) | KDM4ESMN1; SMN2POLBKMT2ATSHR | |
| SCHEMBL28576641 | 0.79 | ERCC1 (0.60) | MAPK14ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL7995185 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HPGDHSD17B10KDM4EPKM | |
| SCHEMBL8322757 | 0.72 | RNASEH1 (0.52) | RNASEH1ALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL7989981 | 0.72 | ALDH1A1 (0.47) | MAPK14ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL28916010 | 0.71 | ERCC1 (0.64) | ALDH1A1HPGDKDM4EPKMSMN1; SMN2 | |
| SCHEMBL28582957 | 0.71 | ERCC1 (0.68) | ALDH1A1HPGDHSD17B10KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |