Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977957 | 0.86 | TOP2A (0.51) | KDM4EALDH1A1TOP2ATOP2BSMN1; SMN2 | |
| SCHEMBL7995926 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1TARBP2SMN1; SMN2TP53 | |
| SCHEMBL7995163 | 0.78 | MMP13 (0.55) | KDM4EALDH1A1TARBP2SMN1; SMN2TP53 | |
| SCHEMBL28582964 | 0.78 | TARBP2 (0.54) | KDM4EALDH1A1TARBP2SMN1; SMN2HSD17B10 | |
| SCHEMBL7989231 | 0.78 | RAB9A (0.47) | KDM4EALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7991775 | 0.78 | ALOX5 (0.59) | KDM4ETARBP2SMN1; SMN2TP53HSD17B10 | |
| SCHEMBL7989585 | 0.78 | TARBP2 (0.46) | KDM4EALDH1A1TARBP2SMN1; SMN2HSD17B10 | |
| SCHEMBL7988588 | 0.77 | PRMT5 (0.58) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL7988569 | 0.75 | ALOX5 (0.48) | KDM4ETARBP2SMN1; SMN2TP53HSD17B10 | |
| SCHEMBL7988441 | 0.74 | AR (0.55) | ALDH1A1TARBP2SMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |