Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | SOD1 | P00441 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GSK3A | P49840 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | QPCT | Q16769 | 4/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5390245 | 0.80 | PRKCA (0.43) | PIM1KDM4EMEN1KMT2AGSK3B | |
| SCHEMBL21637909 | 0.75 | XDH (0.54) | PIM1SOD1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL6936729 | 0.74 | QPCT (0.53) | PIM1KDM4ENAMPTMEN1KMT2A | |
| SCHEMBL7992854 | 0.73 | GPR84 (0.41) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL7989807 | 0.72 | CDC7 (0.39) | MEN1KMT2AGSK3AGSK3BDRD4 | |
| SCHEMBL7993027 | 0.71 | CA1 (0.40) | PIM1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL5375269 | 0.71 | CDC7 (0.43) | GSK3B | |
| SCHEMBL7978450 | 0.71 | GPR84 (0.44) | PIM1KDM4EGSK3B | |
| SCHEMBL7996288 | 0.70 | MTNR1A (0.46) | GSK3AGSK3B | |
| SCHEMBL5380552 | 0.70 | XDH (0.53) | PIM1SMN1; SMN2KDM4ERAB9ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070727-A1 | 2-(ARYLALKYLAMINO)PYRIMIDONE DERIVATIVES AND 2-(HETEROARYLALKYLAMINO)PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | claimed |