Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 16/20 | 0.94 |
| ▸ | MMP2 | P08253 | 5/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979043 | 0.81 | MMP3 (0.65) | MMP3MMP2MMP1MMP9MMP13 | |
| SCHEMBL7997116 | 0.76 | MMP3 (0.69) | MMP3MMP2MMP9 | |
| SCHEMBL7389205 | 0.74 | MMP3 (1.00) | MMP3MMP2MMP1MMP9MMP13 | |
| SCHEMBL7398557 | 0.72 | MMP3 (1.00) | MMP3HDAC1HDAC2 | |
| SCHEMBL7389210 | 0.72 | MMP3 (0.90) | MMP3HDAC1HDAC2 | |
| SCHEMBL7997139 | 0.72 | MMP3 (0.72) | MMP3 | |
| SCHEMBL7398298 | 0.72 | MMP3 (1.00) | MMP3MMP2MMP1MMP9MMP13 | |
| SCHEMBL7487118 | 0.70 | MMP3 (0.65) | MMP3 | |
| SCHEMBL2680423 | 0.69 | MMP3 (1.00) | MMP3MMP2MMP1MMP9MMP13 | |
| SCHEMBL31443147 | 0.69 | MMP3 (0.49) | MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | claimed |
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |