Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 12/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994042 | 0.82 | L3MBTL1 (0.50) | MMP3NPC1SMN1; SMN2MAPTCTSD | |
| SCHEMBL7389205 | 0.82 | MMP3 (1.00) | MMP3MMP2MMP9MMP12MMP14 | |
| SCHEMBL7993608 | 0.76 | MMP3 (0.94) | MMP3MMP2MMP9 | |
| SCHEMBL11841026 | 0.74 | MMP3 (0.55) | MMP3ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL7997188 | 0.72 | MMP3 (0.40) | MMP3NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7990504 | 0.72 | MMP3 (1.00) | MMP3NPC1RAB9A | |
| SCHEMBL7996909 | 0.70 | MMP3 (1.00) | MMP3NPC1RAB9AMTNR1A | |
| SCHEMBL7993470 | 0.70 | MMP3 (0.47) | MMP3ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL7398298 | 0.69 | MMP3 (1.00) | MMP3MMP2MMP9MMP14 | |
| SCHEMBL10345794 | 0.69 | SMN1; SMN2 (0.58) | ALDH1A1NPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |