Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 10/20 | 0.65 |
| ▸ | MMP2 | P08253 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993608 | 0.81 | MMP3 (0.94) | MMP3MMP2MMP1MMP9MMP13 | |
| SCHEMBL7994042 | 0.78 | L3MBTL1 (0.50) | MMP3NPC1ATML3MBTL1MAPT | |
| SCHEMBL7993470 | 0.75 | MMP3 (0.47) | MMP3HPGDNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL7997188 | 0.75 | MMP3 (0.40) | MMP3HPGDNPC1ATML3MBTL1 | |
| SCHEMBL7993523 | 0.74 | MMP3 (0.70) | MMP3MMP2NPC1L3MBTL1MMP9 | |
| SCHEMBL28398723 | 0.70 | NPC1 (0.57) | HPGDNPC1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL7372943 | 0.69 | MAOB (0.89) | MMP2MAOBABCB1HPGDABCG2 | |
| SCHEMBL7392898 | 0.69 | TDP1 (0.54) | HPGDABCG2NPC1ATML3MBTL1 | |
| SCHEMBL28396741 | 0.69 | ALDH1A1 (0.55) | NPC1ATML3MBTL1ALDH1A1 | |
| SCHEMBL17769820 | 0.69 | KMT2A (0.69) | MAOBHPGDNPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |