Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GPX4 | P36969 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711085 | 0.83 | ALDH1A1 (0.53) | RAB9ANPC1ALDH1A1PAX8JAK2 | |
| SCHEMBL1924742 | 0.74 | RAB9A (0.76) | RAB9ANPC1ALDH1A1PAX8JAK2 | |
| SCHEMBL8003755 | 0.72 | TRPM8 (0.66) | RAB9ANPC1ALDH1A1PAX8HTT | |
| SCHEMBL12764035 | 0.72 | TSPO (0.77) | RAB9ANPC1ALDH1A1PAX8JAK2 | |
| SCHEMBL18338252 | 0.71 | RAB9A (1.00) | RAB9ANPC1ALDH1A1PAX8JAK2 | |
| SCHEMBL17324352 | 0.71 | RAB9A (0.44) | RAB9ANPC1ALDH1A1PAX8JAK2 | |
| SCHEMBL378758 | 0.71 | RAB9A (0.56) | RAB9ANPC1ALDH1A1PAX8JAK2 | |
| SCHEMBL9547612 | 0.70 | ALDH1A1 (0.57) | RAB9ANPC1ALDH1A1PAX8JAK2 | |
| SCHEMBL6831396 | 0.69 | RAB9A (0.62) | RAB9ANPC1ALDH1A1PAX8JAK2 | |
| SCHEMBL18425944 | 0.69 | LTB4R2 (0.78) | RAB9ANPC1ALDH1A1PAX8JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944636-A4 | PHENYL GLYOXAMIDES AS sPLA2 INHIBITORS | LILLY CO ELI (US) | 2000-07-12 | — | — | EP | disclosed |
| EP-0944636-A1 | PHENYL GLYOXAMIDES AS sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998024794-A1 | PHENYL GLYOXAMIDES AS sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |