Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MPO | P05164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997354 | 0.74 | GPR84 (0.48) | LMNAALDH1A1KMT2AMPOHTR2A | |
| SCHEMBL7994177 | 0.74 | GPR84 (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7997990 | 0.73 | HTR2A (0.57) | ALDH1A1MAPTMEN1KMT2AMPO | |
| SCHEMBL7995675 | 0.73 | HTR2A (0.57) | ALDH1A1MAPTMEN1KMT2AMPO | |
| SCHEMBL8001578 | 0.73 | HTR2A (0.57) | ALDH1A1MAPTMEN1KMT2AMPO | |
| SCHEMBL4803022 | 0.72 | HTT (0.55) | LMNAALDH1A1HTTMAPTMEN1 | |
| SCHEMBL7993961 | 0.72 | HTR2A (0.53) | MPOHSD17B10MTNR1AMTNR1BHTR2A | |
| SCHEMBL7997830 | 0.72 | HTR2A (0.53) | LMNAMEN1KMT2AMPOHPGD | |
| SCHEMBL7998078 | 0.72 | GPR84 (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7997361 | 0.72 | HTR2A (0.41) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |