Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10252339 | 0.88 | MPO (0.49) | HTTSMN1; SMN2HTR2AMAPTNPSR1 | |
| SCHEMBL13715349 | 0.86 | HTT (0.54) | HTTALDH1A1LMNASMN1; SMN2HTR2A | |
| SCHEMBL14667559 | 0.86 | ALDH1A1 (0.60) | HTTALDH1A1LMNASMN1; SMN2HTR2A | |
| SCHEMBL27911679 | 0.82 | GPR84 (0.59) | HTTALDH1A1LMNASMN1; SMN2HTR2A | |
| SCHEMBL13258467 | 0.82 | MPO (0.64) | SMN1; SMN2HTR2AMAPTNPSR1MPO | |
| SCHEMBL4803628 | 0.81 | HTR2A (0.71) | HTTSMN1; SMN2HTR2AMAPTNPSR1 | |
| SCHEMBL5477550 | 0.81 | MPO (0.49) | HTTSMN1; SMN2HTR2AMAPTNPSR1 | |
| SCHEMBL6131640 | 0.79 | ALDH1A1 (0.57) | HTTALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL11539380 | 0.78 | HTR2A (0.54) | HTTSMN1; SMN2HTR2AMAPTNPSR1 | |
| SCHEMBL4801899 | 0.78 | MPO (0.73) | SMN1; SMN2HTR2AMAPTNPSR1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120302545-A1 | Method of Using PI3K and MEK Modulators | EXELIXIS, INC. (US) | 2012-11-29 | — | — | US | claimed |
| CN-118308790-A | Adjustable double A-site hybrid ferroelectric perovskite single crystal photovoltaic device and preparation method and application thereof | 暨南大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-217262186-U | Safety device for storing 7-ethyl tryptophol | 安徽金泉生物科技股份有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-216320072-U | 7 quick crystallization device of ethyl tryptophol reagent | 安徽金泉生物科技股份有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-11046705-B1 | Method for preparing etodolac methyl ester | ZHEJIANG INTERNATIONAL STUDIES UNIVERSITY (CN) | 2021-06-29 | — | — | US | disclosed |
| CN-208320023-U | A kind of rectifying device applied to 7- ethyl tryptophol | 江苏绿洲化工有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-206508895-U | It is a kind of to be used for the constant temperature agitating device of 7 ethyl tryptophols synthesis | 沈建君 | 2017-09-22 | — | — | CN | disclosed |
| CN-206404672-U | It is a kind of to be used for the multitube pre-mixing apparatus of 7 ethyl tryptophols synthesis | 安徽金泉生物科技股份有限公司 | 2017-08-15 | — | — | CN | disclosed |
| CN-205223070-U | A continuous production system that is used for 7 - ethyl tryptophol synthetic | ANHUI JINQUAN BIOTECHNOLOGY CO LTD | 2016-05-11 | — | — | CN | disclosed |
| EP-2533254-B1 | REDUCING AGENT COMPOSITION FOR CONDUCTIVE METAL PASTE | NAMICS CORP (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-20060166947-A1 | Multiple myeloma treatments | DANA-FARBER CANCER INSTITUTE, INC. | 2006-07-27 | — | — | US | disclosed |
| US-20060160876-A1 | (6-Bromo-1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid ethyl ester; antineoplastic, anti-inflammatory, analgesic | SALMEDIX, INC. | 2006-07-20 | — | — | US | disclosed |
| EP-1680428-A2 | SUBSTITUTED INDOLE DERIVATIVES | CEPHALON, INC. (US) | 2006-07-19 | — | — | EP | disclosed |
| EP-1673373-A2 | INDOLE DERIVATIVES | Salmedix, Inc. (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005033112-A2 | SUBSTITUTED INDOLE DERIVATIVES | CEPHALON, INC. (US) | 2005-04-14 | — | — | WO | disclosed |
| WO-2005033113-A2 | INDOLE DERIVATIVES | CEPHALON, INC (US) | 2005-04-14 | — | — | WO | disclosed |
| US-4409224-A | Pyrimido[1,6-a]indole derivatives | AMERICAN HOME PRODUCTS CORP. (US) | 1983-10-11 | — | — | US | disclosed |
| US-4307234-A | Pyrimido[1,6-a]indole derivatives | AMERICAN HOME PRODUCTS CORP. (US) | 1981-12-22 | — | — | US | disclosed |
| WO-1980000537-A1 | PYRIMIDO(1,6-A)INDOLE DERIVATIVES | AMERICAN HOME PROD (US) | 1980-04-03 | — | — | WO | disclosed |
| EP-0008950-A2 | Pyrimido(1,6-a)indole derivatives and intermediates therefor, processes for their preparation, pharmaceutical compositions containing the derivatives and their use | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160876-A1 | (6-Bromo-1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid ethyl ester; antineoplastic, anti-inflammatory, analgesic | IL6, OPRK1, PTGES3 | HTT 1373/4885ALDH1A1 74/4885LMNA 3106/4885 |
| US-11046705-B1 | Method for preparing etodolac methyl ester | MSMO1, HTR3C, TH | HTT 1660/4885ALDH1A1 1791/4885LMNA 754/4885 |
| US-20120302545-A1 | Method of Using PI3K and MEK Modulators | PIK3CA, PIK3CD, PIK3R1 | HTT 4266/4885ALDH1A1 4089/4885LMNA 3675/4885 |
| US-20060166947-A1 | Multiple myeloma treatments | BCL6, MCL1, BCL6B | HTT 4106/4885ALDH1A1 2355/4885LMNA 1920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.