Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 6/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995803 | 0.78 | SCN9A (0.44) | BRD4 | |
| SCHEMBL8001602 | 0.72 | ALDH1A1 (0.38) | HSP90AA1HSP90B1 | |
| SCHEMBL16935872 | 0.70 | L3MBTL1 (0.38) | — | |
| SCHEMBL4612193 | 0.67 | ITGA4 (0.41) | — | |
| SCHEMBL28854691 | 0.63 | CYP17A1 (0.37) | F2 | |
| SCHEMBL28941159 | 0.63 | PAX8 (0.36) | — | |
| SCHEMBL7983691 | 0.62 | LMNA (0.38) | OPRK1MCL1F2TYMP | |
| SCHEMBL7833383 | 0.61 | CYP2D6 (0.37) | HSP90AA1HSP90B1BRD4 | |
| SCHEMBL18914289 | 0.61 | KMT2A (0.61) | — | |
| SCHEMBL28941291 | 0.61 | S100B (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |