SCHEMBL7995955

SCHEMBL7995955

COC(=O)C=C(C)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
DEGS1 O15121 1/20 0.51
SMN1; SMN2 Q16637 4/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
HPGD P15428 1/20 0.45
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
CES2 O00748 2/20 0.43
CES1 P23141 2/20 0.43
SRC P12931 1/20 0.43
LTB4R Q15722 1/20 0.43
KDM4E B2RXH2 1/20 0.42
NFE2L2 Q16236 1/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10830070 1.00 TSHR (0.52) TSHRDEGS1SMN1; SMN2KMT2AMEN1
SCHEMBL7995954 1.00 TSHR (0.52) TSHRDEGS1SMN1; SMN2KMT2AMEN1
SCHEMBL17073789 0.89 LTB4R (0.54) DEGS1SMN1; SMN2LMNANPC1MAPT
SCHEMBL9660257 0.84 DEGS1 (0.47) TSHRDEGS1SMN1; SMN2KMT2AMEN1
SCHEMBL9335464 0.82 CA1 (0.53) DEGS1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL13864069 0.82 TDP1 (0.53) SMN1; SMN2KMT2AMEN1LMNAHPGD
SCHEMBL18555000 0.82 DEGS1 (0.46) TSHRDEGS1SMN1; SMN2KMT2AMEN1
SCHEMBL9450419 0.82 DEGS1 (0.46) TSHRDEGS1SMN1; SMN2KMT2AMEN1
SCHEMBL5528002 0.82 NFE2L2 (0.57) TSHRSMN1; SMN2KMT2AMEN1HPGD
SCHEMBL4195600 0.82 TSHR (0.54) TSHRSMN1; SMN2KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072151-A1 SELECTIVE PARTIAL REDUCTION OF ESTERS USING GROUP IV TRANSITION METAL CATALYSTS AND USES THEREOF BAYLOR UNIVERSITY (US) 2025-04-03 WO disclosed
US-20250100984-A1 SELECTIVE PARTIAL REDUCTION OF ESTERS USING GROUP IV TRANSITION METAL CATALYSTS AND USES THEREOF BAYLOR UNIVERSITY (US) 2025-03-27 US disclosed
EP-0975224-A1 PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS MONSANTO COMPANY (US) 2000-02-02 EP disclosed
US-6020287-A USING MIXTURE OF HERBICIDE AND PHENYL-SUBSTITUTED OLEFIN COMPOUND MONSANTO COMPANY (US) 2000-02-01 US disclosed
WO-1998033385-A1 PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS MONSANTO COMPANY (US) 1998-08-06 WO disclosed
EP-0279474-B1 PROCESS FOR THE PREPARATION OF AN ESTER OF A 3-ARYL-SUBSTITUTED ACRYLIC ACID SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-09-11 EP disclosed
US-4789756-A REACTING ALKENYL AROMATIC WITH CARBON MONOXIDE AND ALCOHOL SHELL OIL COMPANY (US) 1988-12-06 US disclosed
EP-0279474-A1 Process for the preparation of an ester of a 3-aryl-substituted acrylic acid SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-08-24 EP disclosed
EP-0066518-B1 COMPOUNDS AND METHODS FOR TREATING DEPRESSION MERRELL DOW FRANCE ET CIE (FR) 1986-06-11 EP disclosed
US-4421767-A 3-(HYDROXYPHENYL)-2-AMINO-3-BUTENOIC ACID OR DERIVATIVE MERRELL TORAUDE ET COMPAGNIE (FR) 1983-12-20 US disclosed
EP-0066518-A2 Compounds and methods for treating depression MERRELL DOW FRANCE ET CIE (FR) 1982-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250100984-A1 SELECTIVE PARTIAL REDUCTION OF ESTERS USING GROUP IV TRANSITION METAL CATALYSTS AND USES THEREOF ADH1A, ADH5, ADH1C TSHR 4672/4885DEGS1 238/4885SMN1; SMN2 1264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.