Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735580 | 0.90 | ACLY (0.39) | ACLYFFAR2MAOAADRA1AMAPT | |
| SCHEMBL6790401 | 0.89 | ACLY (0.39) | ACLYFFAR2MAOAADRA1AMAPT | |
| SCHEMBL5735982 | 0.85 | MAOA (0.37) | ACLYFFAR2MAOAADRA1AMAPT | |
| SCHEMBL7998327 | 0.81 | MAPK14 (0.32) | FFAR2BUB1MAPK14 | |
| SCHEMBL5736818 | 0.81 | ACLY (0.39) | ACLYKDM4ENPC1RAB9AMEN1 | |
| SCHEMBL5735113 | 0.80 | GAA (0.43) | ACLYMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL1599472 | 0.80 | ACLY (0.40) | ACLYMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7995977 | 0.79 | ACLY (0.39) | ACLYMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7995986 | 0.78 | MAPT (0.43) | MAPTKDM4ESMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL6790398 | 0.78 | GAA (0.50) | ACLYMAPTKDM4ETP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |