Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92331 | 0.90 | L3MBTL1 (0.56) | L3MBTL1SIGMAR1DDB1CRBNPOLB | |
| Bromide SCHEMBL28426487 | 0.89 | L3MBTL1 (0.54) | L3MBTL1SIGMAR1DDB1CRBNPOLB | |
| Hydrochloric Acid SCHEMBL4768580 | 0.89 | L3MBTL1 (0.54) | L3MBTL1SIGMAR1DDB1CRBNPOLB | |
| SCHEMBL10765650 | 0.83 | L3MBTL1 (0.59) | L3MBTL1HRH3SIGMAR1DDB1CRBN | |
| SCHEMBL4692001 | 0.82 | MEN1 (0.47) | L3MBTL1SIGMAR1POLBCYP2C9CYP2C19 | |
| SCHEMBL25271016 | 0.81 | ALDH1A1 (0.42) | L3MBTL1GRM2HRH3POLBHDAC1 | |
| SCHEMBL14863940 | 0.81 | HTR2C (0.43) | L3MBTL1HRH3SIGMAR1DDB1CRBN | |
| SCHEMBL20129619 | 0.81 | ALDH1A1 (0.42) | L3MBTL1HRH3SIGMAR1POLBKMT2A | |
| SCHEMBL24648953 | 0.81 | MGLL (0.43) | L3MBTL1HRH3MGLLPOLBKMT2A | |
| SCHEMBL2899901 | 0.81 | ALDH1A1 (0.63) | L3MBTL1GRM2POLBCYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |