Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 16/20 | 0.52 |
| ▸ | F10 | P00742 | 14/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.50 |
| ▸ | F2 | P00734 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7997619 | 0.92 | PRSS1 (0.52) | PRSS1F10PRSS2PRSS3F2 | |
| SCHEMBL7999734 | 0.85 | F10 (0.39) | PRSS1F10F2 | |
| SCHEMBL7999929 | 0.78 | HRH3 (0.52) | PRSS1F10F2 | |
| SCHEMBL7996082 | 0.77 | GPR119 (0.42) | PRSS1F10 | |
| SCHEMBL7987038 | 0.74 | F10 (0.54) | PRSS1F10PRSS2PRSS3F2 | |
| SCHEMBL7996357 | 0.74 | NPC1 (0.54) | PRSS1F10PRSS2PRSS3F2 | |
| SCHEMBL7999919 | 0.69 | CYP46A1 (0.39) | — | |
| SCHEMBL7997768 | 0.69 | NPC1 (0.49) | PRSS1F10F2 | |
| SCHEMBL31006725 | 0.69 | HPGD (0.53) | PRSS1F10PRSS2PRSS3 | |
| SCHEMBL7997696 | 0.67 | F10 (0.44) | PRSS1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |