Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572166 | 0.87 | AOX1 (0.45) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL7565049 | 0.85 | AOX1 (0.45) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL7570667 | 0.85 | AOX1 (0.47) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL7568211 | 0.84 | AOX1 (0.53) | AOX1HDAC1HDAC6KDM4EALDH1A1 | |
| SCHEMBL7573613 | 0.80 | TAS1R3 (0.54) | AOX1TAS1R3TAS1R1TAS1R2PTK2 | |
| SCHEMBL7564792 | 0.79 | NPC1 (0.48) | TAS1R3TAS1R1PTK2KDM4EALDH1A1 | |
| SCHEMBL7567392 | 0.78 | CTSS (0.45) | HDAC1HDAC6TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7564033 | 0.77 | HDAC1 (0.40) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL8013624 | 0.75 | MAPT (0.45) | TAS1R3TAS1R1TAS1R2PTK2KDM4E | |
| SCHEMBL7998024 | 0.75 | MAPT (0.45) | TAS1R3TAS1R1TAS1R2PTK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |