Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994363 | 0.83 | TBXAS1 (0.54) | TBXAS1BRD4CYP11B1CYP11B2FTO | |
| SCHEMBL13604557 | 0.81 | KDM4E (0.45) | TBXAS1BRD4CYP19A1CYP17A1KDM4E | |
| SCHEMBL8001577 | 0.79 | BRD4 (0.47) | TBXAS1BRD4CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL3440035 | 0.77 | ALDH1A1 (0.43) | BRD4NPSR1PTGDR2P2RX7BRD9 | |
| SCHEMBL3439958 | 0.77 | ALDH1A1 (0.44) | BRD4POLBP2RX7BRD9 | |
| SCHEMBL4486676 | 0.76 | AGTR2 (0.52) | TBXAS1CYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL3439960 | 0.76 | ALDH1A1 (0.43) | BRD4POLBP2RX7BRD9 | |
| SCHEMBL7997538 | 0.76 | ALDH1A1 (0.47) | BRD4POLBP2RX7BRD9 | |
| SCHEMBL3439997 | 0.75 | CACNA1G (0.41) | BRD4KDM4ENPSR1P2RX7BRD9 | |
| SCHEMBL7998218 | 0.75 | SLC29A1 (0.46) | BRD4P2RX7BRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |