SCHEMBL7998438

SCHEMBL7998438

CCSc1nc2ccccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.73
RAB9A P51151 5/20 0.71
NPC1 O15118 4/20 0.71
TXN P10599 1/20 0.70
SMN1; SMN2 Q16637 5/20 0.68
EPHX2 P34913 1/20 0.65
POLB P06746 2/20 0.64
HPGD P15428 2/20 0.64
KMT2A Q03164 3/20 0.63
MEN1 O00255 2/20 0.63
AR P10275 2/20 0.63
ALDH1A1 P00352 1/20 0.60
TP53 P04637 1/20 0.59
ALOX15 P16050 1/20 0.59
TSHR P16473 1/20 0.59
MAPK1 P28482 1/20 0.59
HSD17B10 Q99714 1/20 0.59
LMNA P02545 2/20 0.58
HTT P42858 2/20 0.58
MAPT P10636 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31175737 1.00 BCHE (0.73) BCHERAB9ANPC1TXNSMN1; SMN2
Bromide SCHEMBL29546581 0.98 BCHE (0.71) BCHERAB9ANPC1TXNSMN1; SMN2
Bromide SCHEMBL2506425 0.98 BCHE (0.71) BCHERAB9ANPC1TXNSMN1; SMN2
SCHEMBL8098342 0.86 RAB9A (0.82) BCHERAB9ANPC1TXNSMN1; SMN2
SCHEMBL11475158 0.85 BCHE (1.00) BCHERAB9ANPC1SMN1; SMN2EPHX2
SCHEMBL425175 0.83 RAB9A (1.00) BCHERAB9ANPC1TXNSMN1; SMN2
SCHEMBL22292431 0.82 BCHE (0.69) BCHERAB9ANPC1TXNSMN1; SMN2
SCHEMBL11307167 0.82 TXN (1.00) BCHERAB9ANPC1TXNSMN1; SMN2
SCHEMBL8425964 0.82 SMN1; SMN2 (0.79) BCHERAB9ANPC1SMN1; SMN2EPHX2
SCHEMBL2948524 0.82 RAB9A (0.91) BCHERAB9ANPC1SMN1; SMN2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4633638-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) Luminous Mind Inc. (US) 2025-10-22 EP claimed
WO-2024130044-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) LUMINOUS MIND INC. (US) 2024-06-20 WO claimed
CN-109659546-B Sulfur/nitrogen/silicon co-doped graphite composite negative electrode material and preparation method thereof 成都爱敏特新能源技术有限公司 2021-11-23 CN claimed
CN-110845910-A OLED ink for ink-jet printing and preparation method thereof 成都新柯力化工科技有限公司 2020-02-28 CN claimed
CN-108101935-A Silane of one kind structure containing benzimidazole and preparation method thereof 烟台大学 2018-06-01 CN claimed
EP-4633638-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) Luminous Mind Inc. (US) 2025-10-22 EP disclosed
EP-4541352-A3 COMPOSITIONS AND METHODS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS Algernon Pharmaceuticals Inc. (CA) 2025-07-16 EP disclosed
EP-4541352-A2 COMPOSITIONS AND METHODS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS Algernon Pharmaceuticals Inc. (CA) 2025-04-23 EP disclosed
EP-4541352-A2 COMPOSITIONS AND METHODS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS Algernon Pharmaceuticals Inc. (CA) 2025-04-23 EP disclosed
US-12280026-B2 Use of repirinast in the prophylaxis or treatment of renal fibrosis or kidney disease ALGERNON PHARMACEUTICALS INC. (CA) 2025-04-22 US disclosed
US-12280026-B2 Use of repirinast in the prophylaxis or treatment of renal fibrosis or kidney disease ALGERNON PHARMACEUTICALS INC. (CA) 2025-04-22 US disclosed
EP-3923938-B1 IFENPRODIL OR RADIPRODIL FOR TREATING IDIOPATHIC PULMONARY FIBROSIS SEYLTX INC (US) 2025-04-16 EP disclosed
EP-2110416-A2 Dispersion of water-insoluble colorant, method of producing substance containing water-insoluble colorant, fine particles of water-insoluble colorant, dispersing agent for water-insoluble colorant, and recording liquid, ink set, printed article, method of forming image and image forming apparatus using the same Fujifilm Corporation (JP) 2009-10-21 EP disclosed
US-20090246481-A1 DISPERSION OF WATER-INSOLUBLE COLORANT, METHOD OF PRODUCING SUBSTANCE CONTAINING WATER-INSOLUBLE COLORANT, FINE PARTICLES OF WATER-INSOLUBLE COLORANT, DISPERSING AGENT FOR WATER-INSOLUBLE COLORANT, AND RECORDING LIQUID, INK SET, PRINTED ARTICLE, METHOD OF FORMING IMAGE AND IMAGE FORMING APPARATUS USING THE SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246481-A1 DISPERSION OF WATER-INSOLUBLE COLORANT, METHOD OF PRODUCING SUBSTANCE CONTAINING WATER-INSOLUBLE COLORANT, FINE PARTICLES OF WATER-INSOLUBLE COLORANT, DISPERSING AGENT FOR WATER-INSOLUBLE COLORANT, AND RECORDING LIQUID, INK SET, PRINTED ARTICLE, METHOD OF FORMING IMAGE AND IMAGE FORMING APPARATUS USING THE SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090214797-A1 INKJET INK COMPOSITION, AND INKJET RECORDING METHOD AND PRINTED MATERIAL EMPLOYING SAME FUJIFILM CORPORATION (JP) 2009-08-27 US disclosed
US-20090214797-A1 INKJET INK COMPOSITION, AND INKJET RECORDING METHOD AND PRINTED MATERIAL EMPLOYING SAME FUJIFILM CORPORATION (JP) 2009-08-27 US disclosed
US-20080125449-A1 SUBSTITUTED DIHYDROPYRIMIDINES, DIHYDROPYRIMIDONES AND DIHYDROPYRIMIDINETHIONES AS CALCIUM CHANNEL BLOCKERS PULLELA PHANI KUMAR 2008-05-29 US disclosed
US-20080125449-A1 SUBSTITUTED DIHYDROPYRIMIDINES, DIHYDROPYRIMIDONES AND DIHYDROPYRIMIDINETHIONES AS CALCIUM CHANNEL BLOCKERS PULLELA PHANI KUMAR 2008-05-29 US disclosed
US-7235570-B2 1,4-dihydropyridine and pyridine compounds as calcium channel blockers VITTAL MALLYA SCIENTIFIC RESEARCH (IN) 2007-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080125449-A1 SUBSTITUTED DIHYDROPYRIMIDINES, DIHYDROPYRIMIDONES AND DIHYDROPYRIMIDINETHIONES AS CALCIUM CHANNEL BLOCKERS ORAI1, RYR2, RYR1 BCHE 3701/4885RAB9A 3136/4885NPC1 1285/4885
US-12280026-B2 Use of repirinast in the prophylaxis or treatment of renal fibrosis or kidney disease INMT, RNMT, MMP1 BCHE 115/4885RAB9A 561/4885NPC1 4116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.