Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | PLK1 | P53350 | 1/20 | 0.64 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | CBS | P35520 | 1/20 | 0.63 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.63 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.63 |
| ▸ | FLT3 | P36888 | 1/20 | 0.62 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.62 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.62 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.62 |
| ▸ | ALPL | P05186 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isowogonin SCHEMBL28012275 | 0.90 | ACHE (0.79) | APPKDM4EMAPTCYP1A1CYP1A2 | |
| SCHEMBL7168992 | 0.88 | ALDH1A1 (0.68) | APPKDM4EPOLBMAPTCYP1A1 | |
| SCHEMBL6359647 | 0.88 | ACHE (0.81) | APPKDM4EPOLBMAPTACHE | |
| SCHEMBL29100197 | 0.84 | APP (0.93) | APPKDM4EMAPTCYP1A1CYP1A2 | |
| SCHEMBL30619516 | 0.84 | APP (0.93) | APPKDM4EMAPTCYP1A1CYP1A2 | |
| SCHEMBL29465666 | 0.84 | APP (1.00) | APPKDM4EPOLBMAPTCYP1A1 | |
| SCHEMBL28986431 | 0.83 | CBS (0.78) | APPKDM4EPOLBMAPTCYP1A1 | |
| SCHEMBL476215 | 0.83 | CBS (0.78) | APPKDM4EPOLBMAPTCYP1A1 | |
| SCHEMBL29435853 | 0.83 | CBS (0.78) | APPKDM4EPOLBMAPTCYP1A1 | |
| 4'-Hydroxywogonin SCHEMBL29455103 | 0.83 | GABRP (0.81) | APPPOLBMAPTACHEPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150408-A | Tart cherry compounds that have antioxidant activity and uses thereof | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2000-11-21 | — | — | US | claimed |
| WO-2000033667-A2 | BIOFLAVONOIDS, ANTHOCYANINS AND PHENOL COMPOUNDS FROM CHERRIES AS ANTIOXIDANTS | MICHIGAN STATE UNIVERSITY (US) | 2000-06-15 | — | — | WO | claimed |
| US-6150408-A | Tart cherry compounds that have antioxidant activity and uses thereof | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2000-11-21 | — | — | US | disclosed |
| WO-2000033667-A2 | BIOFLAVONOIDS, ANTHOCYANINS AND PHENOL COMPOUNDS FROM CHERRIES AS ANTIOXIDANTS | MICHIGAN STATE UNIVERSITY (US) | 2000-06-15 | — | — | WO | disclosed |