Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998811 | 0.94 | LMNA (0.43) | LMNAFBP1PTGES2CA1CA2 | |
| SCHEMBL8002290 | 0.82 | MAOB (0.47) | FBP1PTGES2CA1CA2MAPT | |
| SCHEMBL8004385 | 0.82 | HSD17B3 (0.46) | MAPTHSD17B3 | |
| SCHEMBL7988653 | 0.75 | MAOB (0.41) | LMNAMAPTNFE2L2HSD17B3 | |
| SCHEMBL8002639 | 0.73 | NFE2L2 (0.43) | FBP1PTGES2MAPTNFE2L2HSD17B3 | |
| SCHEMBL8002658 | 0.73 | NFE2L2 (0.45) | FBP1NFE2L2 | |
| SCHEMBL7998895 | 0.72 | NFE2L2 (0.41) | FBP1PTGES2NFE2L2 | |
| SCHEMBL8002652 | 0.72 | L3MBTL1 (0.43) | LMNAFBP1PTGES2MAPTNFE2L2 | |
| SCHEMBL23935305 | 0.70 | HSD17B3 (0.53) | MAPTNFE2L2HSD17B3 | |
| SCHEMBL11536695 | 0.67 | HSD17B3 (0.55) | CA1CA2CA9CA5AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120783-A1 | HIGH AFFINITY INHIBITORS OF HEPATITIS C VIRUS NS3/4A PROTEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2009-10-01 | — | — | WO | disclosed |