Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989468 | 0.91 | NFE2L2 (0.40) | L3MBTL1TACR1MAOBCYP1A1CYP1B1 | |
| SCHEMBL8002290 | 0.89 | MAOB (0.47) | MAOBPTGES2NFE2L2FBP1KMT2A | |
| SCHEMBL7998895 | 0.85 | NFE2L2 (0.41) | PTGES2NFE2L2FBP1 | |
| SCHEMBL7998748 | 0.77 | CYP19A1 (0.41) | MAOBPTGES2PPARGLMNANFE2L2 | |
| SCHEMBL7998811 | 0.76 | LMNA (0.43) | PTGES2LMNANFE2L2FBP1MAPT | |
| SCHEMBL7989475 | 0.73 | NFE2L2 (0.50) | L3MBTL1MAOBCYP1B1LMNANFE2L2 | |
| SCHEMBL7988653 | 0.72 | MAOB (0.41) | MAOBPPARGLMNANFE2L2KMT2A | |
| SCHEMBL8001632 | 0.72 | MAPT (0.48) | MAOBPPARGLMNANFE2L2FBP1 | |
| SCHEMBL8002292 | 0.72 | LMNA (0.40) | PTGES2LMNANFE2L2FBP1MAPT | |
| SCHEMBL28413561 | 0.70 | MAOB (0.51) | MAOBCYP1A1CYP1B1PTGES2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120783-A1 | HIGH AFFINITY INHIBITORS OF HEPATITIS C VIRUS NS3/4A PROTEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2009-10-01 | — | — | WO | disclosed |