Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 5/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039377 | 0.81 | MAOA (0.45) | CES1MAOAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL2320565 | 0.79 | ALDH1A1 (0.47) | CES1MAOAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL1160392 | 0.79 | KDM4E (0.33) | ALDH1A1KDM4EMEN1KMT2A | |
| Water SCHEMBL1033325 | 0.78 | KDM4E (0.32) | ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL1935650 | 0.77 | KDM4E (0.31) | ALDH1A1KDM4E | |
| SCHEMBL10440547 | 0.77 | ALDH1A1 (0.42) | CES1MAOAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8154115 | 0.73 | MAPT (0.43) | CES1MAOAALDH1A1MAPTTDP1 | |
| SCHEMBL4527055 | 0.73 | HTR6 (0.35) | CES1MAOAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11813906 | 0.72 | HTR6 (0.37) | CES1MAOAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL335207 | 0.72 | SRD5A2 (0.43) | CES1MAOAALDH1A1MAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043978-A1 | PHOSPHOLIPID-COATED MICROCRYSTALS FOR THE SUSTAINED RELEASE OF PHARMACOLOGICALLY ACTIVE COMPOUNDS AND METHODS OF THEIR MANUFACTURE AND USE | IDEXX LABORATORIES, INC. (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-2000027369-A1 | PHOSPHOLIPID-COATED MICROCRYSTALS FOR THE SUSTAINED RELEASE OF PHARMACOLOGICALLY ACTIVE COMPOUNDS AND METHODS OF THEIR MANUFACTURE AND USE | IDEXX LABORATORIES, INC. (US) | 2000-05-18 | — | — | WO | disclosed |