Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039377 | 0.80 | MAOA (0.45) | MAPTL3MBTL1ALDH1A1CES1MAOA | |
| SCHEMBL10440547 | 0.76 | ALDH1A1 (0.42) | MAPTKMT2AL3MBTL1HPGDALOX15 | |
| SCHEMBL2320565 | 0.76 | ALDH1A1 (0.47) | MAPTKMT2AALDH1A1MEN1PKM | |
| SCHEMBL6961318 | 0.73 | ALDH1A1 (0.47) | MAPTKMT2AHPGDALDH1A1PKM | |
| SCHEMBL8003247 | 0.73 | CES1 (0.41) | MAPTKMT2AL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL335207 | 0.73 | SRD5A2 (0.43) | L3MBTL1HPGDALOX15HSD17B10ALDH1A1 | |
| SCHEMBL31147237 | 0.73 | SRD5A2 (0.43) | L3MBTL1HPGDALOX15HSD17B10ALDH1A1 | |
| SCHEMBL27447443 | 0.70 | KMT2A (0.43) | MAPTKMT2AHPGDHSD17B10ALDH1A1 | |
| SCHEMBL4029362 | 0.69 | ALDH1A1 (0.44) | POLBL3MBTL1HPGDALOX15HSD17B10 | |
| SCHEMBL11813906 | 0.69 | HTR6 (0.37) | ALDH1A1CES1MAOASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709226-A1 | Coating formulations for thermal papers | CIBA-GEIGY AG (CH) | 1996-05-01 | — | — | EP | claimed |
| US-6143904-A | CONDENSING A BENZOPHENONE COMPOUND WITH A PHENOL OR PHENOL COMPOUND IN PRESENCE OF SULFURIC ACID, WITH REMOVAL OF FORMYL PROTECTIVE GROUP IF PRESENT, TO A PHTHALIDE, CYCLIZING THE PHTHALIDE COMPOUND | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-11-07 | — | — | US | disclosed |
| EP-0646473-B1 | Mixture of colour formers | CIBA GEIGY AG (CH) | 1997-12-29 | — | — | EP | disclosed |
| US-5681791-A | USED IN PRESSURE SENSITIVE AND HEAT SENSITIVE RECORDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1997-10-28 | — | — | US | disclosed |
| EP-0709226-A1 | Coating formulations for thermal papers | CIBA-GEIGY AG (CH) | 1996-05-01 | — | — | EP | disclosed |
| EP-0646473-A1 | Mixture of colour formers | CIBA-GEIGY AG (CH) | 1995-04-05 | — | — | EP | disclosed |