Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003396 | 0.87 | TUBB4A (0.48) | GAAL3MBTL1LMNAMAPTMAPK1 | |
| Benzophenone SCHEMBL9305650 | 0.76 | ALDH1A1 (0.64) | GAAL3MBTL1LMNAMAPTATM | |
| SCHEMBL6728497 | 0.76 | THRA (0.61) | GAAL3MBTL1THRATHRBMAPK1 | |
| SCHEMBL6730923 | 0.75 | KDM5A (0.73) | LMNAMAPTTHRATHRBMAPK1 | |
| SCHEMBL7266961 | 0.72 | MAPT (0.72) | GAAL3MBTL1LMNAMAPTMAPK1 | |
| SCHEMBL6737179 | 0.72 | RARG (0.48) | L3MBTL1ALDH1A1SMN1; SMN2RARG | |
| SCHEMBL5989261 | 0.72 | FDPS (0.34) | L3MBTL1LMNAMAPTMAPK1CYP2C9 | |
| SCHEMBL6736947 | 0.70 | MAPT (0.46) | GAAL3MBTL1LMNAMAPTNPC1 | |
| SCHEMBL11472938 | 0.70 | ATM (0.57) | GAAL3MBTL1LMNAMAPTPPARA | |
| SCHEMBL2868546 | 0.70 | KMT2A (0.61) | NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063815-A | TREATMENT OF METABOLIC DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-16 | — | — | US | disclosed |