Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991105 | 0.90 | MAOA (0.46) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 | |
| SCHEMBL6267693 | 0.74 | CARM1 (0.52) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 | |
| SCHEMBL8641403 | 0.72 | SIGMAR1 (0.45) | CARM1PRMT6PRMT8SIGMAR1AOC3 | |
| SCHEMBL9130530 | 0.72 | AOC3 (0.45) | TAAR1HTR2ACYP2A6CARM1PRMT6 | |
| SCHEMBL3585497 | 0.69 | HTR2A (0.56) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 | |
| SCHEMBL4372177 | 0.68 | CARM1 (0.58) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 | |
| SCHEMBL18641347 | 0.68 | CARM1 (0.58) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 | |
| SCHEMBL8828293 | 0.68 | MAOA (0.50) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 | |
| SCHEMBL18085350 | 0.68 | CARM1 (0.44) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 | |
| SCHEMBL3203375 | 0.67 | AOC3 (0.48) | TAAR1HTR2ACYP2A6CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |