Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003701 | 0.90 | TAAR1 (0.44) | MAOASIGMAR1HTR2ATAAR1CYP2A6 | |
| SCHEMBL8006413 | 0.73 | CARM1 (0.42) | MAOASIGMAR1HTR2ATAAR1CYP2A6 | |
| SCHEMBL8641403 | 0.73 | SIGMAR1 (0.45) | SIGMAR1CARM1PRMT6PRMT8AOC3 | |
| SCHEMBL8828293 | 0.72 | MAOA (0.50) | MAOASIGMAR1HTR2ATAAR1CYP2A6 | |
| SCHEMBL28307957 | 0.71 | MAOA (0.57) | MAOASIGMAR1HTR2ATAAR1CYP2A6 | |
| SCHEMBL28163397 | 0.71 | MAOA (0.63) | MAOASIGMAR1HTR2ATAAR1CYP2A6 | |
| Hydrochloric Acid SCHEMBL17372604 | 0.70 | OPRM1 (0.57) | MAOAHTR2ATAAR1CYP2A6SMN1; SMN2 | |
| SCHEMBL3874218 | 0.70 | SIGMAR1 (0.53) | MAOASIGMAR1HTR2ASMN1; SMN2CARM1 | |
| SCHEMBL29766190 | 0.70 | EPOR (0.54) | MAOAHTR2AHRH1 | |
| SCHEMBL9130530 | 0.69 | AOC3 (0.45) | MAOASIGMAR1HTR2ATAAR1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |