Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 16/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059685 | 0.84 | MCHR1 (0.39) | PYGLMCHR1SMYD3CYP51A1CNR1 | |
| SCHEMBL7997110 | 0.74 | DRD2 (0.38) | PYGLCYP51A1 | |
| SCHEMBL8008794 | 0.73 | STAT6 (0.40) | PYGLCYP51A1 | |
| SCHEMBL19856858 | 0.71 | DRD2 (0.39) | PYGLMCHR1CYP51A1 | |
| SCHEMBL19856857 | 0.71 | DRD2 (0.39) | PYGLMCHR1CYP51A1 | |
| SCHEMBL4056416 | 0.71 | SMYD3 (0.39) | PYGLMCHR1SMYD3CYP51A1 | |
| SCHEMBL8005363 | 0.71 | PYGL (0.41) | PYGLCYP51A1 | |
| SCHEMBL8008787 | 0.71 | DRD2 (0.35) | PYGLMCHR1CYP51A1 | |
| SCHEMBL7995186 | 0.71 | DRD2 (0.35) | PYGLMCHR1CYP51A1 | |
| SCHEMBL4048476 | 0.69 | PYGL (0.41) | PYGLSMYD3CYP51A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111680-A1 | TRPV4 ANTAGONISTS | SMITHLINE BEECHAM CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |