Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | PCNA | P12004 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005538 | 0.87 | ROCK2 (0.41) | MMP9LMNALIPEALDH1A1NPC1 | |
| SCHEMBL14748413 | 0.79 | PDE4B (0.40) | LMNAALDH1A1GAAMAPTHPGD | |
| SCHEMBL8006270 | 0.76 | KMT2A (0.41) | MMP9ALDH1A1HPGDTSHR | |
| SCHEMBL8007014 | 0.76 | MMP9 (0.37) | MMP9LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL8008270 | 0.76 | LMNA (0.54) | LMNALIPEALDH1A1NPC1RAB9A | |
| SCHEMBL8007094 | 0.71 | PDE4A (0.50) | MMP9MAOB | |
| SCHEMBL8012386 | 0.70 | PDE4B (0.34) | ALDH1A1HPGD | |
| SCHEMBL19622171 | 0.69 | TSHR (0.54) | LMNAALDH1A1GAAMAPTHPGD | |
| SCHEMBL2126802 | 0.69 | HSP90AB1 (0.56) | HSP90AB1ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL8010793 | 0.68 | ST14 (0.51) | MMP9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111676-A2 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2009-09-11 | — | — | WO | disclosed |