Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | PYGL | P06737 | 2/20 | 0.36 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 4/20 | 0.35 |
| ▸ | CYP51A1 | Q16850 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995203 | 0.95 | DRD2 (0.37) | DRD2PYGLBCAT1CCKBRCYP51A1 | |
| SCHEMBL8010535 | 0.89 | DRD2 (0.37) | DRD2PYGLBCAT1CCKBRCYP51A1 | |
| SCHEMBL8004902 | 0.87 | DRD2 (0.38) | DRD2PYGLCCKBRCYP51A1HTR2C | |
| SCHEMBL8008199 | 0.85 | DRD2 (0.44) | DRD2PYGLCCKBRCYP51A1DRD3 | |
| SCHEMBL8005363 | 0.83 | PYGL (0.41) | DRD2PYGLBCAT1CYP51A1DRD3 | |
| SCHEMBL7995186 | 0.82 | DRD2 (0.35) | DRD2PYGLCCKBRCYP51A1DRD3 | |
| SCHEMBL8008787 | 0.82 | DRD2 (0.35) | DRD2PYGLCCKBRCYP51A1DRD3 | |
| SCHEMBL4059459 | 0.81 | PYGL (0.38) | DRD2PYGLBCAT1CYP51A1DRD3 | |
| SCHEMBL8004708 | 0.81 | PYGL (0.39) | DRD2PYGLCYP51A1DRD3DRD1 | |
| SCHEMBL4057673 | 0.79 | PYGL (0.39) | DRD2PYGLBCAT1CYP51A1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111680-A1 | TRPV4 ANTAGONISTS | SMITHLINE BEECHAM CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |