Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266502 | 0.83 | AKR1C3 (0.44) | HTTALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL5916381 | 0.78 | LMNA (0.44) | L3MBTL1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL3096724 | 0.78 | ALDH1A1 (0.46) | L3MBTL1HTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8007725 | 0.78 | CPN1 (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2081864 | 0.76 | AKR1C3 (0.67) | TP53L3MBTL1HTTSMN1; SMN2ACP3 | |
| SCHEMBL2081866 | 0.76 | AKR1C3 (0.67) | TP53L3MBTL1HTTSMN1; SMN2ACP3 | |
| Acetic Acid SCHEMBL6905316 | 0.75 | L3MBTL1 (0.59) | TP53L3MBTL1HTTSMN1; SMN2ACP3 | |
| SCHEMBL2509178 | 0.74 | L3MBTL1 (0.65) | L3MBTL1HTTSMN1; SMN2ACP3ALDH1A1 | |
| SCHEMBL6898173 | 0.74 | L3MBTL1 (0.65) | L3MBTL1HTTSMN1; SMN2ACP3ALDH1A1 | |
| SCHEMBL6903563 | 0.74 | POLB (0.51) | TP53L3MBTL1HTTSMN1; SMN2ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028442-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL) PHENOL AS AGONISTS OF THE BETA2 ADRENERGIC RECEPTOR | ALMIRALL, S.A. (ES) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028442-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL) PHENOL AS AGONISTS OF THE BETA2 ADRENERGIC RECEPTOR | ADRB2, ADRB1, ADRA2C | TP53 4518/4885L3MBTL1 4479/4885HTT 4182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.