Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999690 | 0.75 | ALDH1A1 (0.57) | ALDH1A1POLBMAOBHSD17B10KMT2A | |
| SCHEMBL10950183 | 0.74 | ALDH1A1 (0.47) | ALDH1A1POLBMAOBKMT2AGAA | |
| SCHEMBL23616323 | 0.74 | TP53 (0.49) | ALDH1A1L3MBTL1 | |
| SCHEMBL12650560 | 0.73 | MAPK1 (0.45) | ALDH1A1POLBMAOBKMT2AMAPK1 | |
| SCHEMBL8008629 | 0.72 | POLB (0.64) | ALDH1A1POLBKMT2AGAATSHR | |
| SCHEMBL9472002 | 0.72 | ALDH1A1 (0.60) | ALDH1A1POLBHSD17B10KMT2AGAA | |
| SCHEMBL8009232 | 0.72 | PPIB (0.41) | ALDH1A1KMT2AMAPK1TDP1L3MBTL1 | |
| SCHEMBL18970373 | 0.72 | L3MBTL1 (0.59) | ALDH1A1MAOBKMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8575004 | 0.71 | POLB (0.56) | ALDH1A1POLBKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL135305 | 0.70 | CA12 (0.66) | ALDH1A1POLBHSD17B10KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6056939-A | Self-assembling heteropolymetallic chelates as imaging agents and radiopharmaceuticals | BRACCO IMAGING S.P.A. (IT) | 2000-05-02 | — | — | US | disclosed |