Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GPR27 | Q9NS67 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMO | Q99835 | 2/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296409 | 0.87 | TMPRSS4 (0.56) | PPARGTMPRSS4HTTUSP2GPR27 | |
| SCHEMBL7936827 | 0.84 | CYP1A2 (0.56) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL649648 | 0.83 | PPARG (0.49) | PPARGTMPRSS4HTTUSP2GPR27 | |
| SCHEMBL27214418 | 0.82 | HSPD1 (0.61) | PPARGTMPRSS4HTTUSP2ALDH1A1 | |
| Potassium SCHEMBL15568160 | 0.82 | PPARG (0.48) | PPARGTMPRSS4HTTUSP2GPR27 | |
| SCHEMBL15568158 | 0.82 | PPARG (0.48) | PPARGTMPRSS4HTTUSP2GPR27 | |
| SCHEMBL24733339 | 0.81 | ALDH1A1 (0.65) | PPARGTMPRSS4HTTUSP2GPR27 | |
| SCHEMBL3788790 | 0.78 | ALDH1A1 (0.66) | TMPRSS4HTTALDH1A1SMOKCNK3 | |
| SCHEMBL1203522 | 0.78 | SMO (0.80) | HTTALDH1A1SMOKCNK3KCNK9 | |
| SCHEMBL11777773 | 0.78 | GPR27 (0.58) | PPARGTMPRSS4HTTUSP2GPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000042214-A1 | PHOSPHATE RELEASE ENZYME ASSAY | PANTHERIX LTD. (GB) | 2000-07-20 | — | — | WO | disclosed |