Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.57 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMO | Q99835 | 2/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12189620 | 0.94 | MEN1 (0.63) | ALDH1A1SORT1CYP3A4CYP2C9ALOX12 | |
| SCHEMBL12189443 | 0.90 | SMO (0.67) | ALDH1A1SORT1GPR27MEN1KMT2A | |
| SCHEMBL15743581 | 0.89 | ALDH1A1 (0.74) | ALDH1A1CYP3A4CYP2C9ALOX12TMPRSS4 | |
| SCHEMBL15743582 | 0.89 | ALDH1A1 (0.74) | ALDH1A1CYP3A4CYP2C9ALOX12TMPRSS4 | |
| SCHEMBL12700212 | 0.88 | SORT1 (0.58) | ALDH1A1SORT1TMPRSS4MEN1KMT2A | |
| SCHEMBL12189470 | 0.88 | SMO (0.59) | ALDH1A1SORT1MEN1KMT2ASMO | |
| SCHEMBL12189648 | 0.88 | RAB9A (0.61) | ALDH1A1SORT1GPR27MEN1KMT2A | |
| SCHEMBL11887699 | 0.86 | SORT1 (0.57) | ALDH1A1SORT1GPR27MEN1KMT2A | |
| SCHEMBL12189584 | 0.86 | PRSS12 (0.55) | ALDH1A1SORT1GPR27MEN1KMT2A | |
| SCHEMBL12189647 | 0.86 | SORT1 (0.51) | ALDH1A1SORT1GPR27MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11413278-B2 | Compounds and methods for promoting stress resistance | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11413278-B2 | Compounds and methods for promoting stress resistance | HSPA9, ATF4, GPX4 | ALDH1A1 1459/4885SORT1 4078/4885CYP3A4 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.