Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009176 | 0.81 | HTR6 (0.49) | HTR6DRD2GAAKDM4EALDH1A1 | |
| SCHEMBL8016483 | 0.80 | HTR6 (0.57) | RAB9AHTR6DRD2MAPTGAA | |
| SCHEMBL8012319 | 0.78 | HTR6 (0.47) | HTR6DRD2GAAKDM4EALDH1A1 | |
| SCHEMBL1666037 | 0.75 | RAB9A (0.57) | RAB9ADYRK1ACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL4069622 | 0.73 | KMT2A (0.40) | KMT2AHTR6MEN1MAPTGAA | |
| SCHEMBL29500516 | 0.72 | LMNA (0.57) | RAB9ADYRK1AKMT2AMEN1MAPT | |
| SCHEMBL19329479 | 0.72 | RIPK1 (0.63) | RAB9ADYRK1ACSNK2A1KMT2AMEN1 | |
| SCHEMBL18537879 | 0.72 | LMNA (0.57) | RAB9ADYRK1AKMT2AMEN1MAPT | |
| SCHEMBL15676771 | 0.72 | SMN1; SMN2 (0.55) | RAB9AKMT2AMEN1MAPTGAA | |
| SCHEMBL18041785 | 0.69 | TGFBR1 (0.52) | RAB9AKMT2AHTR6MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043254-A | ANTIPROLIFERATIVE AGENT; ENZYME INHIBITOR | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-03-28 | — | — | US | disclosed |