Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | DDX3X | O00571 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013124 | 0.90 | CA2 (0.61) | PGRALDH1A1CA1CA2KMT2A | |
| SCHEMBL4101284 | 0.81 | PGR (0.78) | PGRALDH1A1ARCA1CA2 | |
| SCHEMBL12167777 | 0.79 | PGR (0.92) | PGRALDH1A1ARCA1CA2 | |
| SCHEMBL8010004 | 0.79 | POLB (0.64) | ALDH1A1CA1CA2KMT2AMEN1 | |
| SCHEMBL8248683 | 0.79 | ALDH1A1 (0.65) | PGRALDH1A1CA1CA2MMP1 | |
| SCHEMBL1024534 | 0.79 | ALDH1A1 (0.65) | PGRALDH1A1CA1CA2MMP1 | |
| SCHEMBL15043011 | 0.79 | ALDH1A1 (0.66) | PGRALDH1A1CA1CA2MMP1 | |
| SCHEMBL8009551 | 0.79 | MEN1 (0.53) | PGRALDH1A1CA2KMT2AMEN1 | |
| SCHEMBL893934 | 0.78 | CA2 (0.71) | PGRALDH1A1ARCA1CA2 | |
| SCHEMBL642097 | 0.78 | TSHR (0.59) | ALDH1A1KMT2AMEN1LMNAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035904-A1 | INHIBITORS OF β-LACTAMASES AND USES THEREFOR | NORTHWESTERN UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |