Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | HTR6 | P50406 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.50 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997927 | 0.87 | HTR6 (0.66) | HTR6PKMALDH1A1LMNAKMT2A | |
| SCHEMBL28271796 | 0.83 | HTR6 (0.83) | POLBHTR6PKMALDH1A1LMNA | |
| SCHEMBL20323615 | 0.82 | HTR6 (0.66) | POLBHTR6PKMALDH1A1LMNA | |
| SCHEMBL8010014 | 0.79 | PGR (0.65) | POLBHTR6PKMALDH1A1LMNA | |
| SCHEMBL3973555 | 0.79 | POLB (1.00) | POLBHTR6PKMALDH1A1LMNA | |
| SCHEMBL8013318 | 0.78 | POLB (0.55) | POLBALDH1A1KMT2ACA1CA2 | |
| SCHEMBL8018878 | 0.76 | POLB (0.59) | POLBALDH1A1KMT2ACA1CA2 | |
| SCHEMBL8013124 | 0.76 | CA2 (0.61) | POLBPKMALDH1A1LMNAKMT2A | |
| SCHEMBL2723618 | 0.76 | HTR6 (1.00) | POLBHTR6PKMALDH1A1LMNA | |
| SCHEMBL28509432 | 0.76 | HTR6 (0.75) | POLBHTR6PKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035904-A1 | INHIBITORS OF β-LACTAMASES AND USES THEREFOR | NORTHWESTERN UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |