Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23554861 | 0.74 | CYP3A4 (0.41) | ALOX5LMNAKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL2399005 | 0.74 | KEAP1 (0.53) | ALOX5LMNAKEAP1NFE2L2ALDH1A1 | |
| P-Xylene SCHEMBL2524457 | 0.71 | TDP1 (0.63) | ALOX5LMNAALDH1A1ACHECES2 | |
| P-Xylene SCHEMBL15875989 | 0.71 | TDP1 (0.63) | ALOX5LMNAALDH1A1ACHECES2 | |
| SCHEMBL11861772 | 0.69 | KEAP1 (0.45) | ALOX5LMNAKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL4615333 | 0.69 | ALOX5 (0.53) | ALOX5LMNAALDH1A1CYP2C19ACHE | |
| SCHEMBL7798252 | 0.69 | CHRNA7 (0.41) | ALOX5LMNAKEAP1NFE2L2ALDH1A1 | |
| P-Xylene SCHEMBL28147896 | 0.67 | ALDH1A1 (0.58) | ALOX5LMNAALDH1A1ACHECES2 | |
| SCHEMBL600979 | 0.67 | KEAP1 (0.47) | LMNAKEAP1NFE2L2ALDH1A1ACHE | |
| SCHEMBL28403042 | 0.67 | CES2 (0.52) | LMNAKEAP1NFE2L2ALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000034804-A1 | HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-06-15 | — | — | WO | disclosed |