Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL31252976 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL28757542 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| Potassium Ion SCHEMBL2965805 | 0.87 | KMT2A (0.59) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| Potassium Ion SCHEMBL2983136 | 0.87 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| Potassium Ion SCHEMBL2979884 | 0.87 | KMT2A (0.47) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL2983082 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL10582813 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL7026429 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL8536343 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL2979886 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107988811-B | Flame-retardant polyurethane synthetic leather | 佛山市艾菲特自行车配件有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-112703182-A | Method for preparing 5-iodine-2-carboxylic acid potassium benzene sulfonate | 隆萨解决方案股份公司 | 2021-04-23 | — | — | CN | disclosed |
| CN-107988811-B | Flame-retardant polyurethane synthetic leather | 佛山市艾菲特自行车配件有限公司 | 2020-06-05 | — | — | CN | disclosed |
| US-6127572-A | Process for preparing 2-carboxy-5-nitrobenzenesulfonic acid and salts thereof by oxidation | HOECHST SCHERING AGREVO GMBH (DE) | 2000-10-03 | — | — | US | disclosed |