Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32673908 | 0.70 | LMNA (0.42) | LMNACYP2C9CA12CA1CA2 | |
| SCHEMBL8024205 | 0.69 | LMNA (0.35) | LMNACYP2C9CA12CA1CA2 | |
| SCHEMBL629353 | 0.67 | HIF1A (0.39) | LMNAKDM4EALDH1A1HPGDKLK7 | |
| SCHEMBL10501346 | 0.67 | CA2 (0.36) | CYP2C9CA12CA1CA2CA9 | |
| SCHEMBL11511279 | 0.67 | KDM4E (0.52) | LMNACYP2C9CA12CA1CA2 | |
| SCHEMBL28827972 | 0.65 | ALDH1A1 (0.50) | LMNACYP2C9CA12CA1CA2 | |
| SCHEMBL32674253 | 0.64 | PKLR (0.51) | CA12CA1CA2CA9CA4 | |
| SCHEMBL7914318 | 0.64 | ACHE (0.42) | KDM4EALDH1A1HPGDKLK7 | |
| SCHEMBL7922281 | 0.64 | ACHE (0.38) | LMNAKDM4EALDH1A1HPGDKLK7 | |
| SCHEMBL13363873 | 0.62 | BRD4 (0.32) | KDM4EALDH1A1HPGDKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063202-A2 | BENZO[b] THIOPHENE SULFONAMIDE-1, 1-DIOXIDE DERIVATIVES AND THEIR USE AS ANTINEOPLASTIC AGENTS | UNIVERSIDAD PUBLICA DE NAVARRA (ES) | 2000-10-26 | — | — | WO | disclosed |