Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944942 | 0.93 | RET (0.35) | HTR2ASLC6A4HRH1LMNAMAPT | |
| SCHEMBL7944450 | 0.82 | ALOX12 (0.45) | DRD2DRD4DRD3SMN1; SMN2 | |
| SCHEMBL7946306 | 0.81 | HRH3 (0.34) | HTR2AHRH1HRH3 | |
| SCHEMBL7935365 | 0.78 | LTA4H (0.32) | MAPTHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL7946351 | 0.77 | — | — | |
| SCHEMBL8014096 | 0.76 | ALDH1A1 (0.43) | LMNAALDH1A1CHRM5CHRM1SMPD1 | |
| SCHEMBL7935372 | 0.74 | IDO1 (0.36) | SLC6A4ALDH1A1HTR1ASLC6A2HTR6 | |
| SCHEMBL8013011 | 0.74 | CHRM2 (0.31) | MAPTALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL10403793 | 0.69 | HTR2A (0.30) | HTR2A | |
| SCHEMBL7945043 | 0.69 | AADAT (0.40) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075144-A | ABILITY TO INHIBIT ACETYLCHOLINESTERASE; TREATS ALZHEIMER,S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 2000-06-13 | — | — | US | claimed |