Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023838 | 0.86 | ALOX5 (0.36) | HPGDNPC1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8006519 | 0.82 | POLB (0.41) | MEN1KMT2ANPC1TSHRLMNA | |
| SCHEMBL269871 | 0.76 | ALDH1A1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL15255 | 0.75 | KCNA3 (0.54) | MEN1HPGDKMT2ANPC1TSHR | |
| SCHEMBL3861027 | 0.75 | THRB (0.54) | NPC1TSHRLMNAALOX15MAPK1 | |
| SCHEMBL7062969 | 0.74 | ALDH1A1 (0.39) | MEN1HPGDKMT2ANPC1TSHR | |
| SCHEMBL8006786 | 0.72 | POLB (0.49) | MEN1HPGDKMT2ANPC1TSHR | |
| SCHEMBL819985 | 0.71 | HDAC1 (0.58) | MEN1KMT2ASMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL7430087 | 0.70 | TDP1 (0.56) | MEN1HPGDKMT2ANPC1TSHR | |
| SCHEMBL28009381 | 0.70 | HPGD (0.55) | MEN1HPGDKMT2ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000034804-A1 | HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-06-15 | — | — | WO | disclosed |