Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392778 | 0.81 | MTNR1A (0.50) | ALDH1A1MAPTSMN1; SMN2TSHRRECQL | |
| SCHEMBL8023883 | 0.80 | THRB (0.38) | ALDH1A1MAPTSMN1; SMN2TSHRRECQL | |
| SCHEMBL269871 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRB | |
| SCHEMBL8018649 | 0.74 | MEN1 (0.39) | ALDH1A1MAPTSMN1; SMN2TSHRRECQL | |
| SCHEMBL7529588 | 0.73 | THRB (0.50) | ALDH1A1MAPTSMN1; SMN2TSHRRECQL | |
| SCHEMBL8023838 | 0.73 | ALOX5 (0.36) | ALDH1A1SMN1; SMN2TDP1HPGDKDM4E | |
| SCHEMBL8020679 | 0.73 | THRB (0.41) | ALDH1A1MAPTSMN1; SMN2TSHRRECQL | |
| SCHEMBL8028273 | 0.72 | TDP1 (0.52) | ALDH1A1MAPTSMN1; SMN2TSHRRECQL | |
| SCHEMBL8016747 | 0.72 | THRB (0.45) | ALDH1A1MAPTSMN1; SMN2TSHRRECQL | |
| SCHEMBL10050686 | 0.71 | ELANE (0.55) | ALDH1A1MAPTSMN1; SMN2TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673886-B2 | FOR INTRAOCULAR LENSES | BAUSCH & LOMB INCORPORATED | 2004-01-06 | — | — | US | disclosed |
| US-20020037984-A1 | High refractive index hydrogel compositions for ophthalmic implants | VANDERBILT DAVID P (US) | 2002-03-28 | — | — | US | disclosed |