Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GRK2 | P25098 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018985 | 0.86 | OPRM1 (0.39) | MEN1KMT2APARP1ALDH1A1TDP1 | |
| SCHEMBL8025166 | 0.86 | GAA (0.42) | MEN1KMT2AALDH1A1L3MBTL1NPC1 | |
| SCHEMBL8025266 | 0.81 | TAS1R3 (0.37) | MEN1KMT2ARAB9ABACE1 | |
| SCHEMBL1401073 | 0.74 | PARP1 (0.46) | MEN1KMT2ASMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL8025122 | 0.73 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL1855104 | 0.68 | PARP1 (0.52) | MEN1KMT2ASMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL8020026 | 0.67 | BACE1 (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL20974387 | 0.67 | LMNA (0.39) | MEN1KMT2ASMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL8008104 | 0.66 | KMO (0.55) | MEN1KMT2ASMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL13310394 | 0.65 | HRH3 (0.47) | MEN1KMT2ASMN1; SMN2TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973720-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040344-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |