SCHEMBL8019016

SCHEMBL8019016

CCCC[S+]([O-])Cc1ccc(-c2ccc(CCl)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 3/20 0.35
HRH3 Q9Y5N1 3/20 0.35
HRH4 Q9H3N8 1/20 0.35
RARB P10826 6/20 0.33
HSD17B10 Q99714 2/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
RARA P10276 1/20 0.31
MAPT P10636 1/20 0.31
MTOR P42345 1/20 0.31
KMT2A Q03164 1/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
RAB9A P51151 1/20 0.30
ESR1 P03372 2/20 0.30
ADRA2A P08913 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5690323 0.95 CA2 (0.33) HSD17B10ALDH1A1CA1CA2ESR1
SCHEMBL8021508 0.91 HRH3 (0.40) BDKRB2HRH3HRH4RARBHSD17B10
SCHEMBL5690887 0.88 THRA (0.35) HSD17B10TSHRALDH1A1CA1CA2
SCHEMBL8019206 0.86 ESR1 (0.38) BDKRB2HRH3HRH4HSD17B10ALDH1A1
SCHEMBL17104769 0.77 TP53 (0.39) MEN1KMT2ATP53PTGS2
SCHEMBL27370000 0.75 CALM1 (0.43) TSHRALDH1A1MEN1MAPTKMT2A
SCHEMBL9626222 0.73 TAAR1 (0.37) TSHRALDH1A1MEN1KMT2ANPC1
SCHEMBL8019012 0.73 TSHR (0.32) TSHR
SCHEMBL5074191 0.70 DNM1 (0.43) MEN1KMT2ATP53
SCHEMBL11223470 0.70 DNM1 (0.43) MEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705857-B1 A process for producing polymers of alpha,omega-unsaturated conjugated compounds AVENTIS RES & TECH GMBH & CO (DE) 2000-01-19 EP disclosed
US-5763539-A Process for producing polymers of α,ω-unsaturated conjugated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-09 US disclosed
EP-0705857-A2 A process for producing polymers of alpha,omega-unsaturated conjugated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-10 EP disclosed