SCHEMBL8019012

SCHEMBL8019012

CCCC[S+]([O-])Cc1ccc(C(Cl)[S+]([O-])CCCC)cc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8019206 0.82 ESR1 (0.38)
SCHEMBL5690323 0.77 CA2 (0.33)
SCHEMBL17104769 0.77 TP53 (0.39) MAPK1
SCHEMBL8021508 0.77 HRH3 (0.40) TSHRATM
SCHEMBL8019016 0.73 BDKRB2 (0.35) TSHR
SCHEMBL27370000 0.71 CALM1 (0.43) TSHRMAPK1L3MBTL1
SCHEMBL5690887 0.71 THRA (0.35) TSHR
SCHEMBL11223470 0.70 DNM1 (0.43) MAPK1
SCHEMBL5074191 0.70 DNM1 (0.43) MAPK1
SCHEMBL9245737 0.70 DNM1 (0.43) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705857-B1 A process for producing polymers of alpha,omega-unsaturated conjugated compounds AVENTIS RES & TECH GMBH & CO (DE) 2000-01-19 EP disclosed
US-5763539-A Process for producing polymers of α,ω-unsaturated conjugated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-09 US disclosed
EP-0705857-A2 A process for producing polymers of alpha,omega-unsaturated conjugated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-10 EP disclosed